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January 1, 2008Journal of the Korean Society of Coloproctology

Truncated abstract lacks quantitative results for IGFBP expression in colon cancer versus normal tissue.

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Why the study?

Do tissue IGFBP-2, -3, and -4 levels differ between colon cancer tissue and adjacent normal tissue, and do they correlate with clinicopathologic characteristics?

Population

102 patients with colorectal cancer who underwent operations between January 2004 and December 2006.

Comparison

Measurement of gene expressions of IGFBP-2, -3… vs Adjacent normal colon tissues

Design

Cross-sectional

Key result

The abstract is truncated and does not report quantitative results for the expression of IGFBP-2, -3, and -4 in colon cancer tissue compared to adjacent normal tissue.

Authors

CKChan Dong KimJLJeong Eun LeeBKBo Young Kang

Discussion

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Member takes

Overview

Absence of quantitative results limits immediate clinical utility; leaves open IGFBP roles in colon cancer progression.

Study Design

Type

Observational (n=102)

Structured PICO

Do tissue IGFBP-2, -3, and -4 levels differ between colon cancer tissue and adjacent normal tissue, and do they correlate with clinicopathologic characteristics?

P
Population
102 patients with colorectal cancer who underwent operations between January 2004 and December 2006.
E
Exposure
Measurement of gene expressions of IGFBP-2, -3, and -4 in colon cancer tissue
C
Comparator
Adjacent normal colon tissues
O
Outcome
Difference in tissue IGFBP-2, -3, and -4 levels between colon cancer tissue and adjacent normal tissue, and their association with clinicopathologic characteristics (age, tumor stage, differentiation, serosal invasion, and CEA)surrogate

Cite This Study

Kim et al. (2008) conducted an observational in colon cancer (n=102). Colon cancer tissue vs. Adjacent normal colon tissue was evaluated on Gene expressions of IGFBP-2, -3, -4. The abstract is truncated and does not report quantitative results for the expression of IGFBP-2, -3, and -4 in colon cancer tissue compared to adjacent normal tissue.

synapsesocial.com/papers/6aa8bfa0c697691e3cf41388https://doi.org/10.3393/jksc.2008.24.3.192
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