Key result
Combined chemo, nephrectomy, and radiation yields no 4-month recurrence in pediatric primary renal synovial sarcoma.
Why the study?
Synovial sarcoma originating from the kidney is extremely rare.
Case Report (n=1)
No
A rare case of primary synovial sarcoma of the kidney in a 13-year-old girl was successfully treated with chemotherapy, surgery, and radiation with no recurrence at 4 months.
Supports multimodal therapy in rare pediatric renal synovial sarcoma; hypothesis-generating from single case, needs prospective validation.
Synovial sarcoma originating from the kidney is extremely rare. A 13-year-old girl presented with a mild left flank pain of one-week duration, with no associated history of hematuria or any other systemic symptoms. Computed tomography (CT) demonstrated a 6 × 13 × 9 cm mass in the left kidney. No soft tissue or extrarenal masses were identified. The patient received a combined of treatment with doxorubicin and ifosfamide. A radical nephrectomy was performed in the left kidney with no complications. Postoperative pathology revealed post-chemotherapy residue of monophasic spindle cell synovialosarcoma of the left kidney. She received a combined treatment with doxorubicin and ifosfamide in concomittance with external radiation therapy. The patient was re-examined 4 months after surgery. An abdominal and pulmonary CT found no recurrence or metastasis.
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Ammar et al. (2021) conducted a case report in Primary synovial sarcoma of the kidney (n=1). Doxorubicin, ifosfamide, radical nephrectomy, and external radiation therapy was evaluated on Recurrence or metastasis. Combined treatment with chemotherapy, radical nephrectomy, and radiation therapy resulted in no recurrence or metastasis at 4 months in a 13-year-old girl with primary renal synovial sarcoma.
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