Why the study?
Long-term postoperative outcomes and natural history of complete transposition of the great arteries require evaluation to guide surgical treatment choice.
Does the arterial switch operation improve systemic ventricular function compared to the Mustard operation in patients with complete transposition of the great arteries?
Population
107 cases with transposition of the great arteries
Comparison
Arterial switch operation vs Mustard operation
Design
Observational cohort study
Follow-up
Average 4 years
Key result
Arterial switch operation showed earlier normalization of ejection fraction (≥0.65) and systemic ventricle echocardiographic findings compared to the Mustard operation in long-term survivors.
Authors
Loading...
Supports arterial switch for earlier ventricular recovery in TGA survivors; leaves open need for RCTs to confirm long-term benefit.
Observational (n=107)
Does the arterial switch operation improve systemic ventricular function compared to the Mustard operation in patients with complete transposition of the great arteries?
Long-term postoperative evaluation suggests the arterial switch operation provides better systemic ventricular function than the Mustard operation for complete transposition of the great arteries.
Yokota et al. (1981) conducted an observational in Complete transposition of the great arteries (n=107). Arterial switch operation vs. Mustard operation was evaluated on Ejection fraction and echocardiographic findings of systemic ventricle. Arterial switch operation showed earlier normalization of ejection fraction (≥0.65) and systemic ventricle echocardiographic findings compared to the Mustard operation in long-term survivors.
Synapse has enriched 2 closely related papers on similar clinical questions. Consider them for comparative context: