Key result
Supraclavicular BAT uptake occurs in ~3% of FDG PETs and consistently accompanies mediastinal and suprarenal uptake.
Why the study?
Differentiating brown adipose tissue FDG uptake from malignant uptake in supraclavicular, mediastinal, and suprarenal regions is challenging without CT coregistration.
Population
1495 F-18-FDG PET studies
Comparison
FDG uptake patterns in supraclavicular, paravertebral, mediastinal, and suprarenal BAT regions
Design
Observational study
Authors
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May aid BAT-malignancy differentiation on PET without CT; leaves open prospective validation in oncology cohorts.
Observational (n=1,495)
Concomitant paravertebral and supraclavicular FDG uptake can help differentiate benign brown adipose tissue uptake from malignant uptake on PET imaging when CT coregistration is unavailable.
Kim et al. (2006) conducted an observational in Patients undergoing F-18-FDG PET studies (n=1,495). F-18 FDG uptake in brown adipose tissue was evaluated on Prevalence and concomitance of F-18 FDG uptake in supraclavicular, paravertebral, mediastinal, and suprarenal BAT regions. Among 1,495 F-18-FDG PET studies, supraclavicular BAT uptake was seen in 2.7%, and virtually all mediastinal and suprarenal BAT uptake was associated with supraclavicular and paravertebral uptake.