Key result
Newly diagnosed T2D is linked to early autonomic dysfunction and ~12 bpm higher resting heart rates.
Why the study?
Diabetic autonomic neuropathy is among the least recognized and understood complications of diabetes despite its significant negative impact on survival and quality of life.
Population
100 consecutive newly diagnosed type 2 diabetic patients age 35 to 50 years and 50 normal individuals
Comparison
Newly diagnosed diabetic patients with and without autonomic neuropathy vs controls
Authors
Loading...
Early autonomic dysfunction is detectable at T2DM diagnosis; hypothesis-generating for screening but requires prospective validation before practice change.
Cross-Sectional (n=150)
Yes
Absolute Event Rate: 88.1% vs 76.5%
p-value: p=<0.01
Newly diagnosed type 2 diabetic patients exhibit early signs of cardiovascular autonomic dysfunction compared to healthy controls, suggesting a need for earlier screening.
MD. Eajaz Ahmed Shariff Prakash SB (2019) conducted a cross-sectional in Type 2 Diabetes Mellitus (n=150). Type 2 Diabetes Mellitus vs. Healthy controls was evaluated on Resting heart rate (p=<0.01). Newly diagnosed type 2 diabetic patients had a significantly higher resting heart rate (88.1 vs 76.5 bpm, p<0.01) and decreased Valsalva ratio compared to healthy controls, indicating early cardiovascular autonomic dysfunction.