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May 1, 2003Menopause The Journal of The North American Menopause Society

Postmenopausal women lose less visceral adipose tissue during a weight reduction program

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Key result

Postmenopausal status is linked to less VAT loss during weight reduction versus premenopausal status.

  • n=40

Why the study?

Does a weight reduction program reduce visceral adipose tissue differently in postmenopausal compared to premenopausal obese women?

Population

40 obese women (21 premenopausal and 19 postmenopausal)

Comparison

Weight reduction program including lifestyle… vs Premenopausal obese women undergoing the same…

Design

Cohort

Follow-up

12 weeks

Authors

HPHye S. ParkUniversitat Autònoma de BarcelonaKLKi-Up Lee

Discussion

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Implication

May warrant adjusted weight-loss targets in postmenopausal obesity; hypothesis-generating for menopause-specific effects on visceral fat loss.

Study Design

Type

Cohort (n=40)

Structured PICO

Does a weight reduction program reduce visceral adipose tissue differently in postmenopausal compared to premenopausal obese women?

P
Population
40 obese women (21 premenopausal and 19 postmenopausal) undergoing a 12-week weight reduction program including lifestyle modification and adjuvant pharmacotherapy.
E
Exposure
Weight reduction program including lifestyle modification and adjuvant pharmacotherapy for 12 weeks
C
Comparator
Premenopausal obese women undergoing the same weight reduction program
O
Outcome
Percent change in visceral adipose tissue (VAT) determined by CT scan at the level of L4-L5surrogate

Postmenopausal obese women lose less visceral adipose tissue than premenopausal women during a 12-week weight reduction program, which may make it more difficult to mitigate cardiovascular risk.

Cite This Study

Park et al. (2003) conducted a cohort in Obesity (n=40). Postmenopausal state vs. Premenopausal state was evaluated on Percent change in visceral adipose tissue (VAT). Postmenopausal obese women lost significantly less visceral adipose tissue compared with premenopausal women during a 12-week weight reduction program.

synapsesocial.com/papers/6aa8f8c7e29bd5f6edd29a8ehttps://doi.org/10.1097/00042192-200310030-00009
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Weight gain and cardiovascular risk factors in the post-menopausal woman1997 · 39 citations
  2. 2Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden.1984 · 1,669 citations
  3. 3PATHOGENESIS OF THE INSULIN RESISTANCE SYNDROME (SYNDROME X)1997 · 75 citations
  4. 4Larger Amounts of Visceral Adipose Tissue in Asian Americans2001 · 307 citations
  5. 5A Review of the Association between Abdominal Fat Distribution, Health Outcome Measures, and Modifiable Risk Factors1993 · 70 citations