Key result
Preoperative tumor embolization enables successful resection of a mediastinal paraganglioma in a Fontan patient.
Why the study?
Paraganglioma rarely occurs in the mediastinum, though an association between the Fontan procedure and paragangliomas has been suggested.
Case Report (n=1)
Demonstrates the feasibility and safety of resecting a rare mediastinal paraganglioma in a patient with Fontan circulation using preoperative pulmonary artery occlusion testing and tumor embolization.
May warrant paraganglioma evaluation in post-Fontan hypertension; extends sparse case reports but leaves causal link open.
Paraganglioma is a rare neuroendocrine tumor commonly located in the abdomen, head, and neck but rarely in the mediastinum. An association between the Fontan procedure and paragangliomas has been suggested. We report the case of a 28-year-old female patient incidentally diagnosed with a mediastinal paraganglioma at hypertension evaluation during cardiac catheterization post-Fontan procedure. We performed a preoperative right pulmonary artery occlusion test to ensure safe 1-lung ventilation. The tumor's feeding vessels were embolized to minimize intraoperative blood loss. This case demonstrates successful resection of a mediastinal paraganglioma in a patient with Fontan circulation, using careful preoperative preparation and tumor embolization.
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Sakada et al. (2025) conducted a case report in Mediastinal paraganglioma post-Fontan procedure (n=1). Resection of mediastinal paraganglioma with preoperative tumor embolization was evaluated on Successful resection. Successful resection of a mediastinal paraganglioma in a patient with Fontan circulation was achieved using careful preoperative preparation and tumor embolization.
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