Key result
Short rims in large ASD closure are linked to ~6 minutes longer manipulation but similar redeployment.
Why the study?
The safety and efficacy of intraoperative device closure (IODC) for large secundum atrial septal defects, especially with short rims, required evaluation.
Does intraoperative device closure safely and effectively achieve defect occlusion in patients with large secundum atrial septal defects?
Cohort (n=68)
Does intraoperative device closure safely and effectively achieve defect occlusion in patients with large secundum atrial septal defects?
Absolute Event Rate: 18.9% vs 9.7%
p-value: p=>0.05
Intraoperative device closure via minithoracotomy is a safe and highly effective alternative for large secundum ASDs, achieving 100% mid-term occlusion even in patients with a short rim.
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Short rims prolong manipulation time without raising redeployment risk; extends feasibility data but leaves open randomized confirmation of safety.
Li et al. (2008) conducted a cohort in Large secundum atrial septal defects (n=68). Short rim (≤5 mm) vs. Sufficient rims was evaluated on Redeployment with larger device (p=>0.05). In patients undergoing intraoperative device closure for large ASDs, a short rim (≤5 mm) was associated with longer intracardiac manipulation time (22 vs 16 min; p<0.01) but similar redeployment rates (18.9% vs 9.7%; p>0.05) compared to sufficient rims.
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