Key result
Phylogenetic analysis of Japanese mumps strains reveals well-conserved F proteins and SH gene-consistent clustering.
Population
Mumps virus (MuV) strains isolated in Saitama Prefecture, Japan, from 1997 to 2001
Design
Preclinical
Authors
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Supports mumps strain surveillance in Japan; leaves open whether F conservation affects human vaccine response.
The study characterizes contemporary mumps virus strains in Japan, identifying genotype G as predominant in 2000-2001 and proposing the renaming of a new genotype to K.
Uchida et al. (2003) studied Mumps virus (MuV) strains. SH and F gene nucleotide sequence analysis was evaluated on Genotype characterization and phylogenetic analysis. Phylogenetic analysis of the F gene nucleotide sequences showed that contemporary mumps virus strains in Japan formed clusters consistent with SH gene analysis, with well-conserved F proteins.
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