Key result
Left-dominant coronary anatomy linked to ~75% higher in-hospital mortality in patients undergoing PCI for ACS.
Why the study?
Previous studies indicated that left dominant coronary anatomies are associated with worse prognoses in coronary artery disease, but their impact on in-hospital outcomes after PCI in ACS patients was unclear.
Does left-dominant coronary anatomy worsen in-hospital outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention?
Cohort (n=4,873)
Yes
Does left-dominant coronary anatomy worsen in-hospital outcomes in patients with acute coronary syndrome undergoing percutaneous coronary intervention?
Odds Ratio: 1.75 (95% CI 1.06–2.89)
Absolute Event Rate: 7.8% vs 4.1%
p-value: p=0.030
Left-dominant coronary anatomy is an independent predictor of in-hospital mortality in patients with acute coronary syndrome undergoing percutaneous coronary intervention.
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LD anatomy was associated with higher ACS PCI mortality; hypothesis-generating for dominance-informed risk models before practice change.
Kuno et al. (2013) conducted a cohort in Acute Coronary Syndrome (n=4,873). Left-dominant coronary anatomy vs. Right- or co-dominant coronary anatomy was evaluated on In-hospital mortality (OR 1.75, 95% CI 1.06-2.89, p=0.030). Left-dominant coronary anatomy was an independent predictor of in-hospital mortality (OR 1.75) compared with right- or co-dominant anatomy among patients with acute coronary syndrome undergoing PCI.
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