Key result
Restenosis after CAS is linked to ~498% higher risk of subsequent ipsilateral stroke.
Why the study?
The risk of stroke due to restenosis after carotid artery stenting and independent predictors of restenosis occurrence were not well established.
Does restenosis after carotid artery stenting increase the risk of ipsilateral cerebral infarction, and what are its predictors?
Cohort (n=250)
No
Does restenosis after carotid artery stenting increase the risk of ipsilateral cerebral infarction, and what are its predictors?
Hazard Ratio: 5.98 (95% CI 1.19–24.47)
Absolute Event Rate: 15.8% vs 2.6%
p-value: p=0.032
Restenosis after carotid artery stenting is associated with a significantly increased risk of ipsilateral stroke, and the use of closed cell stents is an independent predictor of restenosis.
Restenosis after CAS was associated with higher late ipsilateral stroke risk; leaves open optimal surveillance and management in this cohort.
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Miyata et al. (2015) conducted a cohort in Carotid artery stenosis (n=250). Restenosis after CAS vs. No restenosis was evaluated on Ipsilateral stroke after the periprocedural period (HR 5.98, 95% CI 1.19-24.47, p=0.032). Restenosis after carotid artery stenting significantly increased the risk of ipsilateral stroke after the periprocedural period (HR 5.98) compared to patients without restenosis.
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