Key result
St. Jude mechanical tricuspid valves show high long-term survival but a ~3% annual thrombosis rate.
Why the study?
The long-term durability and thrombogenicity of the St. Jude Medical valve in the tricuspid position were not well known and required reassessment.
What are the long-term outcomes, durability, and thrombosis rates of the St. Jude Medical valve in the tricuspid position?
Population
23 patients undergoing 25 tricuspid valve replacements with St. Jude Medical valves
Comparison
St. Jude Medical valve in tricuspid position versus bioprosthesis
Design
Cohort study
Follow-up
Mean 11.8 years (range 2.2 to 19.0 years)
Authors
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High thrombosis rate with St. Jude mechanical tricuspid valve warrants caution; leaves open optimal prosthesis choice versus bioprostheses.
Cohort (n=23)
What are the long-term outcomes, durability, and thrombosis rates of the St. Jude Medical valve in the tricuspid position?
The St. Jude Medical mechanical valve in the tricuspid position is associated with higher than expected thrombogenicity, suggesting bioprostheses may be preferable for most patients.
Kawano et al. (2000) conducted a cohort in Tricuspid valve disease requiring replacement (n=23). Tricuspid valve replacement with the St. Jude Medical valve was evaluated on Valve thrombosis (linearized rate per patient-years). Tricuspid valve replacement with the St. Jude Medical valve resulted in an 83% overall survival at 15 years, but a high linearized rate of valve thrombosis (2.9%/patient-years).
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