Key result
ACTN3 and ACE genotypes show no difference between elite sprinters and controls.
Why the study?
Are ACTN3 and ACE genotypes associated with elite sprint athlete status in Jamaican and US African American populations?
Population
Elite Jamaican and US African American sprinters, and controls from the Jamaican and US African American…
Comparison
ACTN3 R577X and ACE I/D and A22982G genotypes vs Controls from the Jamaican and US African…
Design
Case-control
Authors
Loading...
No ACE/ACTN3 link to sprint status in elite Jamaican/US African American athletes; leaves open ancestry-specific genetic influences on performance.
Case-Control (n=732)
Yes
Are ACTN3 and ACE genotypes associated with elite sprint athlete status in Jamaican and US African American populations?
p-value: p=J, P = 0.87; US, P = 0.58
ACTN3 and ACE genotypes are not significant determinants of elite sprint athlete status in Jamaican and US African American populations, partly due to the low underlying frequency of the ACTN3 XX genotype.
Scott et al. (2009) conducted a case-control in Elite sprint athlete status (n=732). ACTN3 and ACE genotypes vs. Population controls was evaluated on ACTN3 genotype distribution (p=J, P = 0.87; US, P = 0.58). ACTN3 and ACE genotypes did not significantly differ between elite Jamaican and US African American sprinters and controls (ACTN3 P=0.87 and P=0.58, respectively).
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: