Key result
ARB therapy offers a safe and tolerable option for managing prehypertension.
Why the study?
Prehypertension is a recognized blood pressure stage but treatment standards have not yet been established.
Does pharmacologic treatment with an angiotensin receptor blocker provide a safe and tolerable option for managing prehypertension?
Does pharmacologic treatment with an angiotensin receptor blocker provide a safe and tolerable option for managing prehypertension?
Pharmacologic treatment with an angiotensin receptor blocker may be a safe and tolerable option for managing prehypertension, expanding beyond traditional nonpharmacologic approaches.
Answers are grounded in this paper and cite their sources.
May support ARB use in prehypertension; leaves open need for outcome trials before practice change.
PURPOSE OF REVIEW: Prehypertension is a recognized stage of blood pressure but treatment standards have not yet been established. This review will focus on the treatment considerations in prehypertension. RECENT FINDINGS: Previous approaches to prehypertensive blood pressure have focused on the role of nonpharmacologic modalities alone. The recently published Trial of Preventing Hypertension (TROPHY) is the first study of pharmacologic intervention in this category of blood pressure. SUMMARY: TROPHY forged new territory in the area of pharmacologic treatment for prehypertension. The safety and tolerability of the angiotensin receptor blocker treatment in the trial offer a new option to clinicians attempting to avoid the ravages of hypertension in the patients they treat. Furthermore the stage is properly set for additional research in treatments for prehypertension.
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Shawna D. Nesbitt (2007) conducted a review in Prehypertension. Angiotensin receptor blocker vs. Nonpharmacologic modalities was evaluated. Pharmacologic treatment with an angiotensin receptor blocker offers a safe and tolerable option for managing prehypertension, as demonstrated by the TROPHY trial.
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