Key result
Body surface isopotential mapping differentiates old anterior MI from normal subjects with ~90% sensitivity.
Why the study?
Does body surface isopotential mapping accurately diagnose old anterior myocardial infarction, including cases without abnormal Q waves?
Observational (n=92)
Yes
Does body surface isopotential mapping accurately diagnose old anterior myocardial infarction, including cases without abnormal Q waves?
Effect estimate: Sensitivity 90%, Specificity 97%
p-value: p=<0.001
Body surface isopotential mapping can effectively distinguish old anterior myocardial infarction, even in patients without diagnostic Q waves on standard ECG, by identifying the location of the minimum potential at 15 msec after QRS onset.
May aid detection of old anterior MI without Q waves; hypothesis-generating and requires prospective validation before clinical use.
正常30例, 異常Q波を有する陳旧性前壁梗塞30例, 異常Q波を有しない陳旧性前壁梗塞32例の体表面電位図を記録し, その極小の位置をQRS開始後5msec毎に比較検討した。正常群と梗塞群の極小の位置は, QRS開始後5, 10, 15, 20, 25msecにおいて危険率0.1%以下の有意差を示した。正常群と, 心電図上診断が容易な異常Q波を有する陳旧性前壁梗塞群あるいは心電図で診断困難な異常Q波を有しない陳旧性前壁梗塞群とはQRS開始後15msecの極小の位置で最もよく区別された。QRS開始後15msecにおいては, 異常Q波を有する梗塞群30例全例の極小が, また, 異常Q波を有しない梗塞群32例では26例の極小が前胸部に位置し, これと異なり正常例では30例中29例の極小が背部に位置した。これらの所見は, 陳旧性前壁梗塞の有無の診断における電位図の有用性を示唆する。
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Hirai et al. (1985) conducted an observational in Old anterior myocardial infarction (n=92). Body surface isopotential mapping vs. Normal subjects was evaluated on Differentiation of old anterior MI from normal subjects based on the location of the minimum at 15 msec after QRS onset (Sensitivity 90%, Specificity 97%, p=<0.001). Body surface isopotential mapping at 15 msec after QRS onset differentiated normal subjects from patients with old anterior myocardial infarction with 90% sensitivity and 97% specificity.
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