Key result
PFA case report details AF ablation in complex venous anatomy with a pacemaker.
Why the study?
Experience using pulsed field ablation for non-pulmonary vein AF triggers is limited, and the effect of direct contact between PFA and indwelling CIED leads is largely unknown.
Case Report
This report describes the use of pulsed field ablation for atrial fibrillation in a complex anatomical case involving persistent left superior vena cava, interrupted inferior vena cava, and a permanent pacemaker.
No outcomes reported; leaves open feasibility, safety, and efficacy of pulsed field ablation in complex venous anatomy with pacemaker.
In 2004, Hsu and colleagues reported persistent left superior vena cava (PLSVC) as a potential source of atrial fibrillation (AF) triggers.1 Pulsed field ablation (PFA) is a non-thermal modality primarily developed to treat AF through pulmonary vein isolation.2 As the first commercial case was in 2021, there is limited experience on the use of PFA for potential non-pulmonary vein sources.2 In addition, the effect of direct contact between PFA and indwelling cardiac implantable electronic device (CIED) leads is largely unknown.
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Wang et al. (2025) conducted a case report in Atrial fibrillation. Pulsed field ablation was evaluated. The abstract provides background for a case of pulsed field ablation for atrial fibrillation in a patient with complex venous anatomy and a pacemaker, without reporting specific clinical outcomes.
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