Key result
Extensive thoracic venous and posterior wall PFA causes no leadless pacemaker interference in case report.
Why the study?
Does extensive pulsed field ablation cause device interference in a patient with a leadless pacemaker?
Case Report (n=1)
No
Does extensive pulsed field ablation cause device interference in a patient with a leadless pacemaker?
This case demonstrates that extensive pulsed field ablation can be safely performed in close proximity to a leadless pacemaker without electromagnetic interference.
Pulsed field ablation near leadless pacemakers may be feasible; single case leaves open broader safety confirmation.
Although Pulsed field ablation (PFA) has demonstrated efficacy for atrial fibrillation, its safety in patients with leadless pacemaker remains uncertain. This case suggests that extensive PFA involving persistent left superior vena cava, superior vena cava, and left atrial posterior wall can be safely performed without device interference.
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Matsuura et al. (2026) conducted a case report in Paroxysmal atrial fibrillation with bradycardia-tachycardia syndrome and a leadless pacemaker (n=1). Extensive Pulsed Field Ablation (PFA) was evaluated on Device interference. Extensive pulsed field ablation involving the persistent left superior vena cava, superior vena cava, and left atrial posterior wall was safely performed without leadless pacemaker interference.
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