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Racemic 2-hydroxymethylthieno[3,2-e:4,5-e′]di[1]benzothiophene with a labile helical structure was converted into a (P) enantiomer upon uptake by bovine serum albumin, in which the existence of two substrate-binding sites with a distinct ability to recognize chirality was revealed.
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Yamada et al. (1994) studied this question.
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