Key result
Mini-electrode catheters cut median PSVT ablation attempts by ~33% and shorten ablation time vs conventional catheters.
Why the study?
Novel ablation catheters equipped with mini-electrodes provide high-resolution mapping, but their performance and efficacy in radiofrequency ablation of paroxysmal supraventricular tachycardias needed evaluation.
Does radiofrequency ablation using mini-electrode catheters reduce ablation attempts and time to ablation endpoints compared to conventional catheters in patients with paroxysmal supraventricular tachycardia?
RCT (n=136)
Does radiofrequency ablation using mini-electrode catheters reduce ablation attempts and time to ablation endpoints compared to conventional catheters in patients with paroxysmal supraventricular tachycardia?
Absolute Event Rate: 2% vs 3%
p-value: p=0.032
The use of mini-electrode-equipped catheters for radiofrequency ablation of PSVT significantly reduces the number of ablation attempts and cumulative ablation time compared to conventional catheters.
Mini-electrode catheters may aid high-resolution PSVT mapping; leaves open whether they improve outcomes versus standard catheters.
INTRODUCTION: Novel ablation catheters equipped with mini-electrodes (ME) offer high resolution mapping for target tissue. This study aimed to evaluate the mapping performance and efficacy of ME catheters in radiofrequency ablation (RFA) of paroxysmal supraventricular tachycardias (PSVTs). METHODS: We prospectively enrolled 136 patients undergoing RFA of PSVT including 76 patients with atrioventricular nodal reentrant tachycardia (AVNRT) and 60 patients with atrioventricular reentrant tachycardia (AVRT) or Wolff-Parkinson-White (WPW) syndrome. Patients were randomized to the ME group (ablation using ME catheters) or the control group (ablation using conventional catheters). The number of ablation attempt and cumulative ablation time to ablation endpoints, which was defined as an emergence of junctional rhythm in AVNRT or accessory pathway (AP) block in AVRT/WPW syndromes were compared. RESULTS: During ablation procedures, discrete slow pathway or AP electrograms were found in 27 (39.7%) patients in the ME group and 13 (19.1%) patients in the control group. The primary study outcomes were significantly lower in the ME group (ablation attempt number: 2.0 [1-4] vs. 3.0 [2-7] in the ME and control group, p = .032; ablation time: 23.5 [5.0-111.5] vs. 64.5 [16.0-185.0] s, p = .013). According to the PSVT diagnosis, ablation time to junctional rhythm was significantly shorter in the ME group in AVNRT. In AVRT/WPW syndrome, both ablation attempt number and ablation time to AP block were nonsignificantly lower in the ME group. CONCLUSION: The novel ME catheter was advantageous for identifying pathway potentials and reducing initial ablation attempt number and ablation time to reach acute ablation endpoint for PSVTs (ClinicalTrials.gov number, NCT04215640).
No takes yet. Share an insight, caveat, or question.
Choi et al. (2022) conducted an RCT in Paroxysmal supraventricular tachycardias (PSVTs) (n=136). Mini-electrode (ME) catheters vs. Conventional catheters was evaluated on Number of ablation attempts to ablation endpoints (p=0.032). Mini-electrode catheters reduced the median number of ablation attempts (2.0 vs 3.0, p=0.032) and ablation time (23.5 vs 64.5 s, p=0.013) compared to conventional catheters for PSVT ablation.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: