Key result
Starvation increases troponin and ER stress gene expression ~2-fold in cricket flight muscle.
Why the study?
Little is known about the mechanism of gene expression changes in skeletal muscle during starvation.
Does starvation alter the expression of troponin complex genes and ER stress associated genes in skeletal muscles of Gryllus bimaculatus?
Does starvation alter the expression of troponin complex genes and ER stress associated genes in skeletal muscles of Gryllus bimaculatus?
This study demonstrates that starvation significantly alters the expression of troponin complex, ER stress-associated genes, and decorin specifically in the dorsal ventral flight muscle of Gryllus bimaculatus.
Answers are grounded in this paper and cite their sources.
Starvation effects limited to cricket flight muscle; leaves open relevance to mammalian cardiac or skeletal biology.
Little is known about the mechanism of gene expression changes in skeletal muscle during starvation. This study investigated the influence of starvation on gene expression of troponin complex (TnC, TnI and TnT), tropomyosin (Tpm), and endoplasmic reticulum (ER) stress associated proteins (BiP, calreticulin, PDI, and ATF6) in three kinds of skeletal muscles of Gryllus bimaculatus. Dorsal ventral flight muscle (DVM), dorsal longitudinal, and dorsal wing flight muscles (DWM) were identified as typical skeletal muscles by H&E staining. Obvious gene expression was detected in the DVM, but not in the DLM or DWM. In addition to gene expression in DVM, gene expression of decorin, a type of myokine, was also significantly increased by starvation. This is the first study that reports the effect of starvation on expression of troponin complex genes and ER stress associated genes in three types of skeletal muscles.
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Kwon et al. (2018) studied Starvation. Starvation vs. Normal breeding conditions with free access to food and water was evaluated on Gene expression of troponin complex and ER stress associated genes in skeletal muscles. Starvation for 3 to 5 days increased the expression of troponin complex and ER stress-associated genes by more than two-fold in the dorsal ventral flight muscle of crickets, but not in other skeletal muscles.
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