Key result
Major head and neck cancer surgery is linked to a ~6% 30-day VTE incidence.
Why the study?
The incidence of venous thromboembolism following major head and neck surgery was not prospectively determined.
Population
47 patients with head and neck cancer after major surgery
Comparison
Observation without routine anticoagulation
Design
Prospective observational cohort study at an academic surgical center
Follow-up
30 days
Authors
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May warrant thromboprophylaxis consideration after major head and neck cancer surgery; leaves open optimal regimens from randomized trials.
Cohort (n=47)
No
The incidence of clinically significant venous thromboembolism in patients undergoing major head and neck cancer surgery without routine anticoagulation was 6% at 30 days, which is slightly higher than previously estimated.
Clayburgh et al. (2013) conducted a cohort in Head and neck cancer (n=47). Major head and neck surgery was evaluated on Total number of new cases of VTE (superficial and deep) identified within 30 days of surgery. Major head and neck surgery in cancer patients was associated with a 6% incidence of clinically significant venous thromboembolism within 30 days postoperatively.
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