Key result
Type 2 diabetes in AMI is linked to ~42% higher blood lactate levels versus non-diabetics.
Why the study?
Does type 2 diabetes increase blood lactate levels and correlate with worse short-term outcomes in patients with acute myocardial infarction?
Population
120 patients divided into three groups of 40: type 2 diabetics with acute myocardial infarction…
Comparison
Type 2 diabetes mellitus in the setting of acute… vs Nondiabetics with acute myocardial infarction…
Design
Cohort
Follow-up
short-term
Authors
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Lactate elevation may identify diabetic AMI patients at higher HF/arrhythmia risk; hypothesis-generating and requires prospective validation.
Observational (n=120)
Does type 2 diabetes increase blood lactate levels and correlate with worse short-term outcomes in patients with acute myocardial infarction?
Absolute Event Rate: 4.54% vs 3.19%
p-value: p=<0.05
High blood lactate levels in diabetic patients with acute myocardial infarction indicate an increased risk for poor outcomes, including heart failure, severe arrhythmias, and mortality.
Jovanović et al. (2016) conducted an observational in Type 2 diabetes and acute myocardial infarction (n=120). Type 2 diabetes vs. Nondiabetics was evaluated on Blood lactate levels (mmol/L) (p=<0.05). Type 2 diabetic patients with acute myocardial infarction had significantly higher blood lactate levels compared to nondiabetics with myocardial infarction (4.54 vs 3.19 mmol/L, p<0.05).
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