Key result
Beta-blockers protect against adrenomedullary overdrive and may modify stress behavior in HTN and IHD.
Why the study?
Stress and sympathetic nervous system hyperactivity contribute to hypertension and ischemic heart disease, but therapeutic advantages of beta-receptor blockers require elucidation.
Do beta-receptor blockers provide protection from stress-induced sympathetic overdrive in patients with hypertension and ischemic heart disease?
Population
Patients with hypertension and ischemic heart disease exposed to stress and sympathetic hypertonicity
Comparison
Beta-receptor blockers versus no beta-blocker therapy or other treatments
Design
Review
Authors
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May support beta-blocker consideration for stress-related sympathetic effects in hypertension and IHD; leaves open confirmation in randomized trials.
Do beta-receptor blockers provide protection from stress-induced sympathetic overdrive in patients with hypertension and ischemic heart disease?
Stress and sympathetic nervous system hypertonicity contribute to hypertension and ischemic heart disease, and beta-blockers may offer protective benefits against these mechanisms.
DeQuattro et al. (1985) conducted a review in Hypertension and Ischemic Heart Disease. Beta receptor blocking agents was evaluated. Beta receptor blocking agents provide protection from adrenomedullary overdrive and may modify behavior related to stress in hypertension and ischemic heart disease.
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