Key result
Higher body-mass index (BMI) is associated with increased von Willebrand factor (VWF) and factor VIII (FVIII) levels, which may protect against bleeding in patients with von Willebrand disease.
Why the study?
Does higher BMI affect VWF and FVIII levels and bleeding phenotype in patients with von Willebrand disease?
Does higher BMI affect VWF and FVIII levels and bleeding phenotype in patients with von Willebrand disease?
Answers are grounded in this paper and cite their sources.
Higher BMI is suggested to be an important determinant of VWF and FVIII levels and bleeding phenotype in patients with von Willebrand disease.
BMI is an important determinant of VWF and FVIII levels and bleeding phenotype in patients with von Willebrand diseaseTo the Editor:In the general population, it has been shown that higher body-mass index (BMI) is associated with increased von willebrand factor (VWF) and factor VIII (FVIII) levels. 1 A higher BMI is also associated with other procoagulant hemostatic changes, and may therefore protect against bleeding.
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Atiq et al. (2019) conducted a letter in von Willebrand disease. Body-mass index (BMI) was evaluated on VWF and FVIII levels and bleeding phenotype. Higher body-mass index (BMI) is associated with increased von Willebrand factor (VWF) and factor VIII (FVIII) levels, which may protect against bleeding in patients with von Willebrand disease.
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