To whom recommend intensive treatment for hypertension?
Key result
Intensive BP targeting <130/80 mmHg reduces major CV events and mortality versus <140/90 mmHg.
Why the study?
The scientific community has long been divided over therapeutic blood pressure targets, particularly considering estimated overall cardiovascular risk, individual risk factors, and associated comorbidities.
Does intensive antihypertensive treatment reduce major cardiovascular events in hypertensive patients?
Population
Hypertensive patients
Comparison
Intensive antihypertensive treatment vs Standard target blood pressure (<140/90 mmHg)
Design
Review
Authors
Discussion
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Member takes
Implication
May refine individualized BP targets in hypertension; leaves open optimal thresholds for high-risk groups.
Structured PICO
Does intensive antihypertensive treatment reduce major cardiovascular events in hypertensive patients?
P
Population
Hypertensive patients
I
Intervention
Intensive antihypertensive treatment (target blood pressure <130/80 mmHg)
C
Comparator
Standard target blood pressure (<140/90 mmHg)
O
Outcome
Major cardiovascular events, myocardial infarction, stroke, heart failure, and all-causes cardiovascular mortalityhard clinical
Intensive blood pressure lowering to <130/80 mmHg, ideally achieved early with combination therapy, is recommended to reduce cardiovascular events in hypertensive patients.
Cite This Study
Volpe et al. (2020) conducted a review in Arterial hypertension. Intensive antihypertensive treatment vs. Standard blood pressure targets (<140/90 mmHg) was evaluated. Intensive antihypertensive treatment targeting blood pressure <130/80 mmHg reduces major cardiovascular events, myocardial infarction, stroke, and mortality compared to a target of <140/90 mmHg.