Why the study?
The effect of nuclear factor-kappa B-1-94 ins/del ATTG and tumour necrosis factor-alpha (-308 G/A) gene polymorphisms on tumour necrosis factor-alpha serum levels and sepsis prognosis was unclear.
Do nuclear factor-kappa B and tumour necrosis factor-alpha gene polymorphisms affect tumour necrosis factor-alpha serum levels in patients with sepsis?
Case-Control (n=176)
Do nuclear factor-kappa B and tumour necrosis factor-alpha gene polymorphisms affect tumour necrosis factor-alpha serum levels in patients with sepsis?
p-value: p=>0.05
The AA genotype and the A allele of the tumour necrosis factor-alpha (-308 G/A) polymorphism may be used as a predictor of elevated tumour necrosis factor-alpha levels in patients with sepsis.
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Mutluer et al. (2017) conducted a case-control in sepsis (n=176). Tumour necrosis factor-alpha (-308 G/A) and nuclear factor-kappa B-1-94 ins/del ATTG gene polymorphisms vs. Healthy controls and patients without the A allele was evaluated on Tumour necrosis factor-alpha serum levels and polymorphism frequencies (p=>0.05).
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