Key result
Heparin-coated stents show preclinical thromboresistance and potential to reduce stent thrombosis and hemorrhagic complications.
Why the study?
Early studies showed high rates of stent thrombosis and bleeding complications from intensive anticoagulation after stent implantation, motivating strategies to reduce stent thrombogenicity.
This review discusses the preclinical and clinical evaluations of heparin-coated stents, which were developed to decrease stent thrombogenicity and reduce the need for intensive anticoagulation.
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May reduce stent thrombosis risk with heparin coating; leaves open need for randomized confirmation before practice change.
Kocsis et al. (2000) conducted a review in Stent thrombosis and hemorrhagic complications. Heparin-coated stents was evaluated. Heparin-coated stents are discussed regarding their preclinical thromboresistance and clinical performance in reducing stent thrombosis and hemorrhagic complications.