Key result
Mixing 5g guar into food lowers postprandial glucose in NIDD, unlike pre-meal drinks.
Why the study?
The effect of different modes of guar administration on postprandial plasma glucose and insulin responses after a starch meal in NIDD patients was unclear.
Does the mode of guar administration (mixed with food vs. pre-meal) affect postprandial plasma glucose and insulin responses in patients with NIDD?
Does the mode of guar administration (mixed with food vs. pre-meal) affect postprandial plasma glucose and insulin responses in patients with NIDD?
Guar is effective at reducing postprandial glucose in NIDD patients only when mixed into food, challenging the recommendation to take it as a pre-meal drink.
Mode of guar administration may influence postprandial glucose in NIDD; leaves open optimal delivery method for clinical use.
The effect of the different modes of guar administration on postprandial plasma glucose and insulin responses after a starch meal was studied in 8 patients with NIDD. They ingested: (a) 30g mashed potato; (b) 5g guar followed by mashed potato; (c) 5g guar mixed with potato. On occasion (c), plasma glucose was significantly decreased, both total and incremental integrated responses (TIR, IIR) being significantly lower. Plasma insulin after (c) was not significantly changed. On occasion (b), neither glucose or insulin values were significantly different from controls. Currently, manufacturers recommend having guar as a pre‐meal drink. In contrast, this study suggests that guar is only effective when mixed into the food.
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Fuessl et al. (1986) studied Non-Insulin Dependent Diabetes (NIDD) (n=8). Guar administration (mixed with food vs pre-meal) vs. 30g mashed potato alone was evaluated on Postprandial plasma glucose and insulin responses. Guar administration (5g) significantly decreased postprandial plasma glucose responses in patients with NIDD only when mixed into food, but not when taken as a pre-meal drink.
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