Key result
RALAR scale improves objective risk assessment for anastomotic leakage after colorectal cancer surgery.
Why the study?
Risk factors for anastomotic leakage after surgical treatment of colorectal cancer were not comprehensively analyzed across multiple studies.
What are the risk factors for anastomotic leakage in patients after surgical treatment of colorectal cancer?
Systematic Review
What are the risk factors for anastomotic leakage in patients after surgical treatment of colorectal cancer?
The RALAR scale improves the objective assessment of anastomotic leakage risk in patients undergoing surgical treatment for colorectal cancer.
Risk stratification may inform AL prevention in colorectal surgery; leaves open prospective validation of RALAR before practice change.
This systematic literature review analyzes the risk factors for anastomotic leakage (AL) in the surgical treatment of colorectal cancer. Based on 42 studies, key risk predictors for AL were identified. The incidence of AL in the studies included in this review ranged from 2,8% to 24,7%. The introduction of the RALAR scale significantly improved the objective assessment of AL risk. A comprehensive approach to prevention, based on risk stratification and treatment personalization, can significantly improve the outcomes of surgical treatment for colorectal cancer.
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Shamanov et al. (2025) conducted a systematic review in Colorectal cancer. Risk factors for anastomotic leakage was evaluated on Anastomotic leakage. In a systematic review of 42 studies, the incidence of anastomotic leakage after colorectal cancer surgery ranged from 2.8% to 24.7%, with the RALAR scale improving objective risk assessment.
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