Key result
Witnessing a husband's fatal cardiac arrest is linked to Takotsubo cardiomyopathy in a 60-year-old woman.
Why the study?
The overall mechanism of Takotsubo cardiomyopathy remains unclear, and this case highlights its classic presentation mimicking acute coronary syndrome along with its diagnostic criteria.
Case Report (n=1)
This case report illustrates the classic clinical presentation of Takotsubo cardiomyopathy and its similarity to acute coronary syndrome.
Case report on Takotsubo adds to sparse literature; leaves open questions on mechanisms and targeted therapies beyond standard HF care.
Takotsubo cardiomyopathy is a form of non-ischemic cardiomyopathy characterized by transient systolic dysfunction. The prevalence of Takotsubo cardiomyopathy has been estimated to be about 2% overall but about 10% amongst women presenting with clinical manifestations of acute coronary syndrome. The overall mechanism of the disease still remains unclear. However, treatment of Takotsubo cardiomyopathy appears to be similar to congestive heart failure (CHF) medical management. This case highlights the classic presentation exhibited very similar to acute coronary syndrome and diagnostic criteria for Takotsubo (stress-induced) cardiomyopathy.
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To et al. (2022) conducted a case report in Takotsubo cardiomyopathy (n=1). Severe emotional stress was evaluated. A 60-year-old woman developed Takotsubo cardiomyopathy, confirmed by apical akinesia and non-obstructive coronary arteries, immediately after the severe emotional stress of witnessing her husband's fatal cardiac arrest.
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