Key result
Cardiac troponin T remains elevated for at least 43 days following orthotopic heart transplantation.
Why the study?
Measurement of serum cardiac troponin T may provide a sensitive and specific method to characterize myocardial cell damage after orthotopic heart transplantation.
Cohort (n=19)
Cardiac troponin T continues to be released for months after orthotopic heart transplantation, indicating ongoing myocardial damage independent of perioperative ischemia.
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Clinicians should interpret post-transplant troponin levels with caution; this leaves open the contribution of ongoing myocardial injury to long-term graft outcomes.
Zimmermann et al. (1993) conducted a cohort in Orthotopic heart transplantation (n=19). Orthotopic heart transplantation was evaluated on Concentration of circulating troponin T. Following orthotopic heart transplantation, cardiac troponin T reached a mean maximum of 3.6 micrograms/l at 7.1 days and remained elevated for at least 43 days in all patients.
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