Key result
Continuous UFH resolves nonobstructive mechanical aortic valve thrombosis and enables healthy delivery in one case.
Why the study?
Pregnant women with mechanical prosthetic heart valves have an increased risk for thromboembolic events, requiring careful management of valve thrombosis.
Does unfractionated heparin successfully treat nonobstructive mechanical valve thrombosis in pregnant women?
Case Report (n=1)
No
Does unfractionated heparin successfully treat nonobstructive mechanical valve thrombosis in pregnant women?
Unfractionated heparin can be successfully used to treat nonobstructive mechanical valve thrombosis during early pregnancy.
May support heparin infusion as an option in early pregnancy with nonobstructive mechanical valve thrombosis; leaves open need for prospective data before practice change.
Introduction: In pregnant women with mechanical prosthetic heart valves one of the most important changes is the increased risk for thromboembolic events. Case report: We report a case of nonobstructive aortic prosthetic valve thrombosis in early pregnancy. The patient was successfully treated with unfractioned heparin. Conclusion: Our case is an example of the successful use of unfractionated heparin in a pregnant women with nonobstructive mechanical valve thrombosis. With this case we review the treatment of prosthetic valve thrombosis during pregnancy, and prevention (with oral and parentheral anticoagulant therapy) according to 2017 ESC/EACTS guidelines for the management of valvular heart disease.
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Biljana Obrenović-Kirćanski (2018) conducted a case report in Mechanical valve thrombosis during pregnancy (n=1). Unfractionated heparin (UFH) was evaluated on Resolution of valve thrombosis and pregnancy outcome. Continuous infusion of unfractionated heparin successfully treated nonobstructive mechanical aortic valve thrombosis in a pregnant woman, leading to a healthy delivery.
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