Key result
Normotensive diabetes is linked to a ~56% higher absolute prevalence of asymptomatic diastolic dysfunction.
Why the study?
LV diastolic dysfunction is an early sign of myocardial involvement in diabetes and an important predictor of heart failure and long-term mortality, but its prevalence in asymptomatic diabetic patients is not well defined.
Does diabetes increase the prevalence of diastolic dysfunction in asymptomatic normotensive patients compared to healthy controls?
Case-Control (n=150)
No
Does diabetes increase the prevalence of diastolic dysfunction in asymptomatic normotensive patients compared to healthy controls?
Asymptomatic normotensive diabetic patients have a significantly higher prevalence of echocardiographic diastolic dysfunction compared to healthy controls, highlighting the potential utility of early screening.
Answers are grounded in this paper and cite their sources.
May warrant screening evaluation in normotensive diabetics; extends cross-sectional evidence but remains hypothesis-generating.
LV diastolic dysfunction is one of the earliest signs of myocardial involvement in diabetes and hence,an important component in diabetic cardiomyopathy.It is also an important predictor of heart failure and longterm mortality. Diabetics have a 2.5 fold inceased risk of heart failure.It is suggested that early detection of diastolic dysfunction by echocardiography can lead to institution of early measures for prevention of heart failure.The aim of this study is to find the prevalence of diastolic dysfunction in asymptomatic diabetic patients by echocardiography.
No takes yet. Share an insight, caveat, or question.
Subhasish Singh (2021) conducted a case-control in Asymptomatic normotensive diabetes (n=150). Diabetes Mellitus vs. Healthy non-diabetic controls was evaluated on Prevalence of diastolic dysfunction (p=<0.05). Asymptomatic diastolic dysfunction was present in 68% of normotensive diabetic patients compared to only 12% of healthy non-diabetic controls (p<0.05).
Synapse has enriched 10 related papers. Consider them for comparative context: