What does this research mean for the field?

In pediatric Wolff-Parkinson-White syndrome, supraventricular tachycardia presenting in infancy resolves in 93% but recurs in 31% around age 8, whereas tachycardia present after age 5 persists in over 75% of patients. Novelty: ClaimNovelty.INCREMENTAL. Consensus alignment: ConsensusAlignment.NEUTRAL.

What question did this study set out to answer?

To evaluate the natural history, early resolution, and late recurrence of supraventricular tachycardia in pediatric patients diagnosed with Wolff-Parkinson-White syndrome.

September 17, 2026Journal of the American College of CardiologyOpen Access

Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: Early disappearance and late recurrence

Q: What is the clinical evidence from this study?

Study design: Cohort. Population: Wolff-Parkinson-White syndrome (n=140). Intervention: Age at onset of supraventricular tachycardia. Primary outcome: Clinical course of tachycardia (disappearance, persistence, and recurrence).

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Key result

In pediatric WPW, infantile SVT typically resolves whereas later onset associates with 78% persistence.

n=140

Population

140 patients with Wolff-Parkinson-White syndrome and initial supraventricular tachycardia before age 18 years

Design

Retrospective review

Follow-up

Mean 7 years

Authors

JPJames C. PerryUniversity of San Diego AGArthur GarsonPediatric / Congenital Cardiology

Discussion

Member takes

Implication

Clinical follow-up reveals early resolution and subsequent recurrence of tachycardia in pediatric Wolff-Parkinson-White syndrome, highlighting the need for long-term monitoring.

Key Points

To evaluate the natural history, early resolution, and late recurrence of supraventricular tachycardia in pediatric patients diagnosed with Wolff-Parkinson-White syndrome.
Longitudinal clinical follow-up of pediatric patients diagnosed with Wolff-Parkinson-White syndrome and supraventricular tachycardia.
Serial electrocardiographic and clinical assessments to monitor accessory pathway conduction, symptom cessation, and subsequent arrhythmia recurrence through childhood.
Supraventricular tachycardia episodes frequently resolve during infancy or early childhood in patients with Wolff-Parkinson-White syndrome.
Late recurrence of tachycardia is observed in a notable subset of patients during later childhood or adolescence despite initial clinical resolution.

Study Design

Type

Cohort (n=140)

PICO

Population

140 patients with Wolff-Parkinson-White syndrome who had their initial episode of supraventricular tachycardia before 18 years of age, evaluated for tachycardia recurrence and persistence.

Exposure / Comparator

Age at onset of supraventricular tachycardia

Primary Outcome

Clinical course of tachycardia (disappearance, persistence, and recurrence)

Cite This Study

Perry et al. (1990) conducted a cohort in Wolff-Parkinson-White syndrome (n=140). Age at onset of supraventricular tachycardia was evaluated on Clinical course of tachycardia (disappearance, persistence, and recurrence). In children with Wolff-Parkinson-White syndrome, supraventricular tachycardia beginning in infancy disappeared in 93% but reappeared in 31%, whereas tachycardia onset after age 5 persisted in 78%.

synapsesocial.com/papers/6aab5b7628c522ff1f5d4dd2 https://doi.org/10.1016/0735-1097(90)90555-4

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Implication

Clinical follow-up reveals early resolution and subsequent recurrence of tachycardia in pediatric Wolff-Parkinson-White syndrome, highlighting the need for long-term monitoring.

Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: Early disappearance and late recurrence

Discussion

Member takes

Implication

Key Points

Study Design

PICO

Cite This Study

Supraventricular tachycardia due to Wolff-Parkinson-White syndrome in children: Early disappearance and late recurrence

Discussion

Member takes

Implication

Key Points

Study Design

PICO

Cite This Study

Also Consider

Also Consider