Key result
Nifedipine plus labetalol safely controls BP during ECT without shortening seizure duration.
Why the study?
The optimum clinical management of elderly patients undergoing ECT who exhibit sustained blood pressure elevations despite labetalol treatment is unclear.
Does combining nifedipine with labetalol safely control blood pressure in elderly depressed patients undergoing ECT who are inadequately controlled by labetalol alone?
Comparison
Combination of nifedipine with labetalol vs labetalol alone
Design
Case report
Follow-up
During ECT treatment
Authors
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Should not yet change ECT BP protocols in elderly patients; hypothesis-generating case report warrants prospective trials.
Case Report (n=10)
Does combining nifedipine with labetalol safely control blood pressure in elderly depressed patients undergoing ECT who are inadequately controlled by labetalol alone?
Combining nifedipine with labetalol appears safe for controlling blood pressure during ECT in elderly patients unresponsive to labetalol alone.
Figiel et al. (1993) conducted a case report in Depression requiring ECT (n=10). Nifedipine combined with labetalol was evaluated on Safety and efficacy (blood pressure control, adverse effects, seizure duration). Combining nifedipine with labetalol safely controlled blood pressure during ECT in 10 elderly patients without causing adverse effects or shortening seizure duration.
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