Why the study?
Does esmolol or nitroglycerin reduce the haemodynamic response during electroconvulsive therapy compared to placebo?
Population
82 electroconvulsive treatments
Comparison
Esmolol 2 mg/kg or nitroglycerin 3 micrograms/kg… vs Placebo given shortly after suxamethonium and 2…
Design
RCT, randomly assigned
Follow-up
1 min after therapy
Authors
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Esmolol may be preferred over nitroglycerin to blunt ECT haemodynamic surges; extends RCT evidence for procedural beta-blockade.
Does esmolol or nitroglycerin reduce the haemodynamic response during electroconvulsive therapy compared to placebo?
Esmolol 2 mg/kg is more effective than nitroglycerin 3 mcg/kg or placebo in controlling the haemodynamic response to electroconvulsive therapy.
O’Flaherty et al. (1992) studied this question.
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