Why the study?
Does esmolol reduce autonomic hypersensitivity and length of seizures in patients undergoing electroconvulsive therapy?
Population
20 patients, ASA physical status I-III undergoing electroconvulsive therapy (ECT)
Comparison
Esmolol infusion vs Placebo infusion
Design
RCT, randomized study, involving four match-pair trials, double-blind
Follow-up
15 minutes
Authors
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Esmolol blunts post-ECT tachycardia but shortens seizures; challenges routine use pending confirmation of preserved efficacy.
Does esmolol reduce autonomic hypersensitivity and length of seizures in patients undergoing electroconvulsive therapy?
Esmolol effectively controls the hyperdynamic response to ECT but also reduces the length of seizures, which may impact ECT efficacy.
Howie et al. (1990) studied this question.
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