Why the study?
Does esmolol bolus and infusion attenuate increases in blood pressure and heart rate during electroconvulsive therapy in ASA physical status I-II patients?
Population
17 ASA physical status I-II patients undergoing electroconvulsive therapy (ECT)
Comparison
Esmolol 80 mg bolus followed by 24 mg.min-1… vs Alternative treatment in a crossover design
Design
RCT, randomized within-patient, crossover design
Follow-up
up to 4 minutes after ECT
Authors
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Supports esmolol bolus and infusion to blunt hemodynamic surges in ECT; confirms RCT efficacy in ASA I-II patients and extends evidence for acute beta-blockade.
Does esmolol bolus and infusion attenuate increases in blood pressure and heart rate during electroconvulsive therapy in ASA physical status I-II patients?
Esmolol bolus and infusion effectively and safely attenuates the acute cardiovascular response (increases in heart rate and blood pressure) during electroconvulsive therapy.
Kovač et al. (1990) studied this question.
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