Key result
Concurrent cancer during coronary angiography is linked to ~450% higher one-year mortality versus non-cancer patients.
Why the study?
With improved cancer-specific survival, cardiovascular toxicities and comorbidities in cancer patients require close attention, especially during inpatient care involving coronary angiography.
Does the presence of cancer affect the outcomes and PCI results in patients requiring coronary angiography during hospitalization?
Cohort (n=306)
Yes
Does the presence of cancer affect the outcomes and PCI results in patients requiring coronary angiography during hospitalization?
Hazard Ratio: 5.5 (95% CI 3–10.2)
Absolute Event Rate: 46% vs 8%
p-value: p=<0.001
Hospitalized cancer patients requiring coronary angiography have comparable PCI results to non-cancer patients but face significantly higher mortality, emphasizing the need for prompt diagnostic clarification and optimal revascularization.
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High mortality in cancer patients undergoing coronary angiography warrants individualized cardio-oncology evaluation; leaves open whether targeted risk strategies improve outcomes.
Mrotzek et al. (2020) conducted a cohort in Coronary artery disease in cancer patients (n=306). Concurrent cancer vs. Matched non-cancer patients was evaluated on 1-year all-cause mortality (HR 5.5, 95% CI 3.0-10.2, p=<0.001). Concurrent cancer in patients undergoing coronary angiography was associated with a significantly higher 1-year all-cause mortality compared to matched non-cancer patients (46% vs. 8%, HR 5.5).
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