Key result
SARS-CoV-2 infection linked to acute myocarditis requiring heart transplantation in pediatric DCM.
Why the study?
The clinical course and management of acute myocarditis in paediatric patients with pre-existing dilated cardiomyopathy following SARS-CoV-2 infection are not well characterized.
Case Report (n=1)
SARS-CoV-2 infection can trigger acute myocarditis and severe decompensation in pediatric patients with pre-existing dilated cardiomyopathy, potentially necessitating heart transplantation.
A 10-year-old child with stabilised idiopathic dilated cardiomyopathy was admitted to the hospital with sudden worsening of heart failure. Further analysis showed increased NT-proBNP and positive for COVID-19. Myocarditis secondary to COVID-19 was assumed. Recurrent hospitalizations with inotropic support were required due to the progressive worsening of cardiac function. Seven months after SARS-CoV-2 myocarditis, she underwent heart transplantation.
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Suarez et al. (2024) conducted a case report in Acute myocarditis and dilated cardiomyopathy (n=1). SARS-CoV-2 infection was evaluated on Heart transplantation. SARS-CoV-2 infection in a 10-year-old girl with pre-existing dilated cardiomyopathy led to acute myocarditis and progressive heart failure requiring heart transplantation 7 months later.
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