Key result
Frailty syndrome is linked to worse early quality of life in elderly ACS patients.
Why the study?
There are few studies regarding the relationship between frailty syndrome and quality of life in elderly patients with acute coronary syndrome.
Does frailty syndrome negatively impact early quality of life in elderly patients with acute coronary syndrome?
Observational (n=91)
Does frailty syndrome negatively impact early quality of life in elderly patients with acute coronary syndrome?
Effect estimate: β -0.277
p-value: p=0.026
Frailty syndrome is highly prevalent in elderly ACS patients and independently predicts worse early quality of life, highlighting the need for routine frailty assessment to guide care.
May inform early QoL expectations in frail elderly ACS; leaves open prospective validation before practice change.
BACKGROUND: Frail elderly people are at risk of developing adverse health outcomes such as disability, hospitalization, and mortality. In recent years, the literature has drawn attention to the role of frailty syndrome (FS) in acute coronary syndrome (ACS). There are few studies regarding the relationship between two multidimensional variables such as FS and quality of life (QoL). OBJECTIVE: The aim of the study was to investigate the relationship between FS and early QoL of elderly patients with ACS (≥65 years old). METHODS: The study was conducted among 91 patients aged 65 years and over with ACS. The MacNew questionnaire was used to evaluate QoL and the Tilburg frailty indicator to evaluate frailty. RESULTS: FS was present in 82.4% of patients. The average Tilburg frailty indicator score was 7.43±2.57. A negative correlation between the global values of FS and QoL was shown (r=-0.549, P<0.05). The vulnerability factors that negatively affected early QoL were: FS, marital status, conservative therapy, and hypertension. In multivariate analysis, FS was found to be the independent predictor of worse QoL (β ± standard error -0.277±0.122, P=0.026). CONCLUSION: The presence of FS has a negative impact on early QoL in patients with ACS. The study suggests that in elderly patients with ACS, there is a need to identify frailty in order to implement additional therapeutic and nursing strategies in ACS.
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Uchmanowicz et al. (2016) conducted an observational in Acute coronary syndrome (n=91). Frailty syndrome was evaluated on Early quality of life (QoL) (β -0.277, p=0.026). Frailty syndrome was an independent predictor of worse early quality of life in elderly patients with acute coronary syndrome (β -0.277, P=0.026).
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