Key result
Frailty is linked to ~320% higher mortality in older patients undergoing cardiac catheterization or PCI.
Why the study?
The authors hypothesized that poor quality of life is highly prevalent in frail older adults and is associated with worse prognosis.
Are frailty and poor quality of life associated with worse long-term survival in older patients undergoing cardiac catheterization or PCI?
Cohort (n=1,550)
Are frailty and poor quality of life associated with worse long-term survival in older patients undergoing cardiac catheterization or PCI?
Effect estimate: HR 4.20 (95% CI 2.63-6.68)
p-value: p=<0.001
Frailty and poor quality of life are highly co-prevalent and independently associated with increased 3-year mortality and MI in older patients undergoing cardiac catheterization or PCI.
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Frailty may inform risk stratification before PCI in older adults; leaves open whether frailty-targeted interventions improve survival.
Kanwar et al. (2020) conducted a cohort in percutaneous coronary intervention and cardiac catheterization (n=1,550). Frailty and poor quality of life vs. Without frailty and poor quality of life was evaluated on 3-year all-cause death (HR 4.20, 95% CI 2.63-6.68, p=<0.001). Frailty was significantly associated with increased 3-year all-cause death (HR 4.20; 95% CI 2.63-6.68; P<0.001) in older patients undergoing cardiac catheterization or PCI.
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