Key result
Higher maternal avian encephalomyelitis antibody titers link to increased progeny viral resistance reaching ~100%.
Why the study?
The correlation between serum antibody titers in vaccinated breeding hens and the resistance of their progeny embryos to avian encephalomyelitis virus challenge was investigated.
Observational
Higher maternal serum antibody titers for avian encephalomyelitis virus correlate with increased resistance to viral challenge in progeny embryos.
May guide maternal vaccination in poultry; hypothesis-generating for titer thresholds before commercial adoption.
Serum antibody titers for avian encephalomyelitis virus of vaccinated breeding hens were correlated with the resistance of the hens' progeny embryos to viral challenge. All of the embryos from hens that had enzyme-linked immunosorbent assay titers greater than 400 were resistant to challenge, and two-thirds of the embryos from hens that had titers greater than 300 were resistant. About one-half of the embryos from hens that had titers from 100 to 300 were immune to challenge.
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Garrett et al. (1985) conducted an observational in Avian encephalomyelitis virus (AEV). Serum antibody titer for AEV vs. Different titer levels (e.g., >400 vs >300 vs 100-300) was evaluated on Resistance of progeny embryos to viral challenge. Higher maternal serum antibody titers for avian encephalomyelitis virus correlated with increased resistance of progeny embryos to viral challenge, with 100% resistance at ELISA titers >400.
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