April 1, 1988European Heart Journal
Quantitation of aortic regurgitation by colour coded cross-sectional Doppler echocardiography
Key result
Cross-sectional Doppler echocardiography shows 84% agreement with angiography for grading aortic regurgitation severity.
- contingency coefficient 0.81
- P<0.00001
- n=60
Why the study?
The reliability of cross-sectional Doppler echocardiography for quantitating aortic regurgitation compared to angiography was examined.
Does colour coded cross-sectional Doppler echocardiography reliably quantitate aortic regurgitation compared to angiography in patients with aortic regurgitation?
Population
60 patients with aortic regurgitation
Comparison
Colour coded cross-sectional Doppler echocardiography vs angiography using Grossman's classification
Design
Observational cross-sectional study
Authors
Discussion
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Member takes
Implication
May support noninvasive Doppler echocardiography for aortic regurgitation assessment; leaves open prospective validation against angiography.
Study Design
Type
Observational (n=60)
Structured PICO
Does colour coded cross-sectional Doppler echocardiography reliably quantitate aortic regurgitation compared to angiography in patients with aortic regurgitation?
P
Population
60 patients with aortic regurgitation undergoing evaluation by angiography and cross-sectional Doppler echocardiography.
E
Exposure
Colour coded cross-sectional Doppler echocardiography (ratio of cross-sectional area of the jet divided by the cross-sectional area of the left ventricular outflow tract)
C
Comparator
Angiography (Grossman's classification)
O
Outcome
Agreement in grading severity of aortic regurgitation between Doppler echocardiography and angiographysurrogate
Main Result
Effect estimate: contingency coefficient 0.81
p-value: p=<0.00001
Colour coded cross-sectional Doppler echocardiography is a reliable noninvasive method for the quantitative evaluation of aortic regurgitation.
Limitations
- Measurement was only possible in 50 patients (83%)
Cite This Study
Baumgartner et al. (1988) conducted an observational in Aortic regurgitation (n=60). Cross-sectional Doppler echocardiography vs. Angiography was evaluated on Agreement between cross-sectional Doppler echocardiography and angiography in grading aortic regurgitation severity (contingency coefficient 0.81, p=<0.00001). Cross-sectional Doppler echocardiography showed complete agreement with angiography in 84% of patients for quantitating aortic regurgitation severity (contingency coefficient 0.81, P<0.00001).