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September 17, 2026Antibody TherapeuticsOpen Access

Dual-component CAR T cell therapy: targeting BCMA with convertible CAR and MicAbodies

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Authors

CTChaitanya TondepuAWAndrew WongCWClifford Wong

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Cite This Study

Tondepu et al. (2026) studied this question.

synapsesocial.com/papers/6aabb6725f706d05830e4e44https://doi.org/10.1093/abt/tbag049
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Abstract 3618: High-avidity BCMA CAR and high-affinity, non-cleavable CD16 Fc receptor incorporated in off-the-shelf CAR T cells promote multi-antigen targeting and durable anti-tumor cytotoxicity in the treatment of multiple myeloma2024 · 1 citations
  2. 2Data from Bicistronic CAR T Cell against BCMA and CD229 Effectively Controls Myeloma Even When BCMA Expression Is Limited2025
  3. 3CAR-modified marrow infiltrating lymphocytes efficiently target malignant plasma cells with very low antigen density2026
  4. 4Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma2024 · 4 citations
  5. 5Engineering BCMA CAR T cells for myeloma-targeted cargo delivery2024 · 1 citations