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September 17, 2026Nutrition and DiabetesOpen Access

Apolipoprotein A-IV deficiency rewires renal fibroblast states and intercellular communication during early obesity-associated chronic kidney disease

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Authors

YWYang WeiTZTing ZhangYJYingying Jin

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Cite This Study

Wei et al. (2026) studied this question.

synapsesocial.com/papers/6aabb6725f706d05830e4f41https://doi.org/10.1038/s41387-026-00468-0
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Single-cell transcriptomics reveals apolipoprotein A4-mediated metabolic-immune reprogramming in lymphocytes during early obesity-related chronic kidney disease.2025 · 2 citations
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  3. 3Apolipoprotein A5 deficiency aggravates high‐fat diet‐induced obesity due to impaired central regulation of food intake2013 · 17 citations
  4. 4Deficiency of apoA-IV in Female 129X1/SvJ Mice Leads to Diet-Induced Obesity, Insulin Resistance, and Decreased Energy Expenditure2023 · 3 citations
  5. 5Single-cell RNA sequencing reveals a novel inhibitory effect of ApoA4 on NAFL mediated by liver-specific subsets of myeloid cells2022 · 18 citations