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September 17, 2026European Journal of Preventive Cardiology

Sex disparities persist in cardiovascular disease management and outcomes.

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Key result

Sex disparities in cardiovascular disease management and outcomes remain a persistent gap that refuses to close.

Authors

MGMartha GulatiCBC Noel Bairey-Merz

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Overview

Clinicians should audit sex-specific CVD care; extends CLARIFY registry data but leaves open effective equity interventions.

Key Points

  • To examine and address the enduring disparities between men and women in the clinical presentation, management, and outcomes of stable coronary artery disease.
  • Evaluation of findings from the prospective observational CLARIFY registry alongside contemporary literature on sex-specific cardiovascular care.
  • Assessment of diagnostic strategies, medical therapy adherence, and clinical endpoint reporting stratified by patient sex.
  • Women with stable coronary artery disease consistently experience different symptom profiles and receive less guideline-directed medical therapy than men.
  • Sex-specific gaps in cardiovascular trial enrollment and clinical registries remain stubbornly persistent despite widespread awareness efforts.

Cite This Study

Gulati et al. (2026) studied this question. Sex disparities in cardiovascular disease management and outcomes remain a persistent gap that refuses to close.

synapsesocial.com/papers/6aabb8135f706d05830e7a1chttps://doi.org/10.1093/eurjpc/zwag488
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Also Consider

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  1. 1Stable or not, woman or man: is there a difference?2012 · 6 citations
  2. 2From background to solutions: Eliminating sex gaps in clinical electrophysiology practice2022 · 1 citations
  3. 3The continuing gender gap in cardiovascular disease: What are we missing in clinical practice?2024 · 1 citations
  4. 4Gender Differences in the Management of Coronary Artery Disease: Bias or Good Clinical Judgment?1992 · 41 citations
  5. 5Cardiovascular disease outcomes: does physician’s sex matter?2026