Why the study?
Nonatheromatous causes of cerebral infarction predominate in young adults, with cardiac emboli being the most frequent identifiable cause, but unusual causes remain underreported.
Case Report (n=1)
Highlights unusual causes of stroke in young adults, including potential cardiac and infectious etiologies.
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Consider syphilis in young stroke patients with murmurs; single case leaves open broader prevalence and screening needs.
Cerebral infarction in the young adult is uncommon. Nonatheromatous causes for stroke preponderate in young adults, in contrast to cerebral infarction in the older population. When a cause can be identified, cardiac emboli are most frequently responsible, with rheumatic valvular disease, atrial arrhythmias, and bacterial endocarditis the most common underlying conditions; congenital heart disease is a rare association. REPORT OF A CASE A 33-year-old man was admitted because of the sudden onset of nonfluent aphasia, right hemiparesis, and transient loss of vision in the left eye. Cardiac findings included a grade 2/6 systolic murmur heard best at the lower left sternal border, a grade 1/6 pansystolic murmur heard in the left axilla, and a diastolic sound at the lower left sternal border, thought to be a tricuspid flow murmur. Neurologic examination disclosed nonfluent aphasia and mild right hemiparesis. A VDRL serologic test was positive in the 1:65 dilution. The FTA-ABS
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Philip E. Newman (1980) conducted a case report in Cerebral infarction (n=1).
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