Key result
Avoiding potentially inappropriate medications linked to absence of postoperative delirium in a single surgical case.
Why the study?
Postoperative delirium can be prevented in high-risk geriatric patients by avoiding potentially inappropriate medications guided by risk stratification and cognitive assessment.
Does the avoidance of potentially inappropriate medications prevent postoperative delirium in geriatric surgical patients?
Case Report (n=1)
Does the avoidance of potentially inappropriate medications prevent postoperative delirium in geriatric surgical patients?
Preoperative cognitive assessment and avoidance of potentially inappropriate medications can prevent postoperative delirium in high-risk geriatric surgical patients.
Single case supports PIM avoidance in geriatric surgery; hypothesis-generating and should not yet change practice.
We demonstrate the utility of risk stratification for postoperative delirium in geriatric patients and show that postoperative delirium can be prevented in high-risk patients when potentially inappropriate medications (PIMs) (medications that are best avoided in older adults) are avoided. In this case, a 65-year-old woman underwent two debridement procedures with similar presurgical risk for postoperative delirium. There was no risk stratification or preoperative cognitive assessment in the first procedure, she received PIMs and developed postoperative delirium. In the second procedure, PIMs were intentionally avoided and postoperative delirium did not occur. This case supports recent recommendations from the European Society of Anaesthesiology, the American Society of Anesthesiologists and the American Geriatrics Society that providers assess a patient's cognitive function and delirium risk profile preoperatively to appropriately guide perioperative management.
No takes yet. Share an insight, caveat, or question.
Burfeind et al. (2021) conducted a case report in postoperative delirium (n=1). Avoidance of potentially inappropriate medications (PIMs) vs. Administration of PIMs was evaluated on postoperative delirium. Avoidance of potentially inappropriate medications prevented postoperative delirium in a 65-year-old woman undergoing a second debridement procedure, compared to her first procedure where PIMs were given.
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: