Key result
5 cmH2O EPAP during slow deep breathing increases high-frequency and reduces low-frequency HRV in COPD.
Why the study?
The acute effects of expiratory positive airway pressure on cardiac autonomic modulation during spontaneous and slow deep breathing in COPD patients were not well characterized.
Does 5 cmH2O expiratory positive airway pressure improve cardiac autonomic modulation in patients with moderate-to-very severe COPD during spontaneous and slow deep breathing?
Population
17 patients with moderate-to-very severe COPD
Comparison
With vs without 5 cmH2O expiratory positive airway pressure during spontaneous and slow deep breathing
Design
Physiological study analyzing heart rate variability during breathing maneuvers
Authors
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May enhance vagal tone acutely in COPD; hypothesis-generating and requires larger trials before practice change.
Does 5 cmH2O expiratory positive airway pressure improve cardiac autonomic modulation in patients with moderate-to-very severe COPD during spontaneous and slow deep breathing?
p-value: p=<0.001
Application of 5 cmH2O expiratory positive airway pressure during spontaneous and slow deep breathing acutely improves cardiac autonomic control in patients with moderate-to-very severe COPD.
Silva et al. (2020) studied chronic obstructive pulmonary disease (n=17). Expiratory positive airway pressure vs. Without expiratory positive airway pressure was evaluated on Low frequency and high frequency heart rate variability indices (p=<0.001). Application of 5 cmH2O expiratory positive airway pressure during slow deep breathing significantly reduced low frequency and increased high frequency heart rate variability in COPD patients (p<0.001).
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